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Table 6 Relation between MPO and Histones levels with the clinical characteristics of APLS patients’ group

From: Insight into antiphospholipid syndrome: the role and clinical utility of neutrophils extracellular traps formation

 

Histones (ng/ml)

P-value

Median (IQR)

Range

Thrombotica

No

2.68 (2.16–3.2)

1.79–10.73

0.000**

Yes

7.79 (4.61–9.76)

2.31–15.79

1ry/2ry APLSa

1ry

7.07 (3.2–9.66)

1.79–15.79

0.42

2ry

4.61 (3.46–8.7)

2.15–12.95

Number of lab Positive Autoantibodieb

Single positivity

2.4 (2.16–4.07)

2.06–9.76

0.006**

Double positivity

7.16 (3.46–9.39)

3.07–10.73

Triple positivity

7.24 (4.12–9.66)

1.79–15.79

 

MPO (ng/ml)

P-value

Median (IQR)

Range

Thrombotica

No

3.73 (2.57–5.9)

1.43–8.76

0.001**

Yes

7.62 (5.56–11.51)

1.79–16.92

1ry/2ry APLSa

1ry

6.21 (4.08–10.22)

2.04–16.92

0.446

2ry

7.23 (5.39–11.73)

1.43–16.54

Number of lab Positive Autoantibodiesb

Single positivity

4.12 (3.13–7.3)

2.04–11.51

0.073**

Double positivity

7.6 (5.56–8.02)

1.43–9.94

Triple positivity

7.43 (5.39–11.73)

1.79–16.92

  1. P-value > 0.05: Non-significant; P-value < 0.05*: Significant; P-value < 0.01**: Highly significant, a: Mann-Whitney test; b: Kruskall-Wallis’s test